We hope you have learned basic informaton about osteoporosis in this module. Please select the correct answer for the following questions.
1. A 45-year old woman undergoes bilateral oophorectomy (ovary removal) which leads to expression of RANK receptors on the surface of some bone cells. What is the most likely consequence of this response ? (Please select one option)
A. Increased bone resorption
B. Decreased osteoid formation
C. Decreased mineralization
D. Osteocyte apoptosis
E. Decreased blood flow to the bone
2. A 65-year-old woman presents to her internist with a chief complaint of acute back pain since reaching down to pick up a 10lb bag of sugar two days ago. She says the pain is excruciating and comments she has trouble walking. Her past medical treatment consists of long-term rheumatoid arthritis for which she has been treated with indomethacin, methotrexate and prednisone, and hypothyroidism, for which she receives levothyroxine. Which of the following most likely contributed to this fracture ? (Please select one option)
A. Rheumatoid arthritis progression
B. Methotrexate side effect
C. Prednisone side effect
D. Indomethacin side effect
E. Levothyroxine side effect